HPV self-testing with same-day treatment for cervical precancer in Mozambique
A hybrid type III effectiveness-implementation, pragmatic intervention trial for cervical cancer screen and treat in Mozambique
['FUNDING_U01'] · TULANE UNIVERSITY OF LOUISIANA · NIH-11400595
This project offers women in Mozambique the option to collect their own HPV test and get quick treatment when needed to catch and treat precancer early.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TULANE UNIVERSITY OF LOUISIANA (nih funded) |
| Locations | 1 site (NEW ORLEANS, UNITED STATES) |
| Trial ID | NIH-11400595 on ClinicalTrials.gov |
What this research studies
You would be offered an HPV self-swab that you can do in your own time or at a clinic, which is then tested for high-risk HPV types. Women who test positive would be linked to a screen-and-treat approach so precancerous lesions can be treated promptly, often the same day. The project tests practical ways to deliver this program across clinics and communities in Mozambique so more women can access screening. The team builds on earlier local work showing self-collection is acceptable and focuses on making the program work in routine care.
Who could benefit from this research
Good fit: Women eligible for cervical cancer screening in Mozambique (typically ages 25–49) who are willing to do a self-collected HPV test or attend a participating clinic would be ideal candidates.
Not a fit: People outside the program’s target age range, women who cannot access participating sites, or those unwilling to perform self-sampling may not receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this could make screening and same-day treatment more available, lowering the chance of cervical cancer and deaths for participating women.
How similar studies have performed: Previous pilot work in Mozambique and WHO guidance support HPV testing and self-collection, and early local studies showed the approach is feasible and preferred by many participants.
Where this research is happening
NEW ORLEANS, UNITED STATES
- TULANE UNIVERSITY OF LOUISIANA — NEW ORLEANS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOON, D. TROY — TULANE UNIVERSITY OF LOUISIANA
- Study coordinator: MOON, D. TROY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus, Cancer Control