How yolk sac microRNAs influence brain development in embryos
Yolk Sac MicroRNAs Regulate Brain Development
This study is looking at tiny molecules called microRNAs in the yolk sac during early pregnancy to see how they help with brain development and nutrient exchange between mom and baby, which could lead to better understanding and prevention of conditions like autism and ADHD.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10935958 on NIH RePORTER |
What this research studies
This research investigates the role of microRNAs in the yolk sac and their impact on brain development during early pregnancy. It focuses on understanding how these microRNAs regulate maternal-fetal nutrient exchange and the migration of cells that contribute to the formation of the brain. By studying the mechanisms involved in neural tube closure, the research aims to uncover critical factors that could prevent neurodevelopmental disorders such as autism and attention deficit disorder. The approach includes analyzing the effects of maternal health on embryonic development and the potential for microRNAs to influence these processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are expectant mothers, particularly those with concerns about neurodevelopmental disorders in their children.
Not a fit: Patients who are not pregnant or those whose pregnancies are not at risk for neurodevelopmental disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing neurodevelopmental disorders in infants.
How similar studies have performed: Other research has shown promising results in understanding the role of maternal health on fetal development, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Keuls, Rachel Anne — Baylor College of Medicine
- Study coordinator: Keuls, Rachel Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.