How yolk sac microRNAs influence brain development in embryos
Official title: Yolk Sac MicroRNAs Regulate Brain Development
Funded at Baylor College of Medicine · NIH-10935958 · Data updated 2026-11-12
This study is looking at tiny molecules called microRNAs in the yolk sac during early pregnancy to see how they help with brain development and nutrient exchange between mom and baby, which could lead to better understanding and prevention of conditions like autism and ADHD.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 17, 2023 |
| Project end | August 16, 2025 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 5F31HD110243-02 |
| Project ID | NIH-10935958 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are expectant mothers, particularly those with concerns about neurodevelopmental disorders in their children.
✕Less likely to help
Patients who are not pregnant or those whose pregnancies are not at risk for neurodevelopmental disorders may not benefit from this research.
What this research studies
This research investigates the role of microRNAs in the yolk sac and their impact on brain development during early pregnancy. It focuses on understanding how these microRNAs regulate maternal-fetal nutrient exchange and the migration of cells that contribute to the formation of the brain. By studying the mechanisms involved in neural tube closure, the research aims to uncover critical factors that could prevent neurodevelopmental disorders such as autism and attention deficit disorder. The approach includes analyzing the effects of maternal health on embryonic development and the potential for microRNAs to influence these processes.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing neurodevelopmental disorders in infants.
How similar studies have gone: Other research has shown promising results in understanding the role of maternal health on fetal development, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Keuls, Rachel Anne — Baylor College of Medicine
- Study coordinator: Keuls, Rachel Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.