How yeast cells sense and respond to glucose levels

Receptor-mediated glucose sensing in yeast

NIH-funded research Columbia International University · NIH-10974735

This study looks at how yeast cells sense and use glucose, which is an important energy source, to help us learn more about how our own bodies manage glucose.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionColumbia International University NIH-funded
Lab location1 site (Columbia, United States)
Project IDNIH-10974735 on NIH RePORTER

What this research studies

This research investigates the mechanisms by which yeast cells detect and respond to glucose, a vital energy source. By using the yeast S. cerevisiae as a model, the study aims to understand how these cells adapt their metabolic pathways based on the availability of glucose. The research focuses on the role of specific glucose transporters and transcription factors in regulating glucose uptake and metabolism. Insights gained from this research could have implications for understanding glucose regulation in higher organisms, including humans.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals with metabolic disorders, particularly those related to glucose regulation.

Not a fit: Patients who do not have metabolic disorders or conditions related to glucose metabolism may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and potential treatments for metabolic disorders like diabetes.

How similar studies have performed: Other research has shown success in understanding glucose sensing mechanisms in various organisms, suggesting that this approach may yield valuable insights.

Where this research is happening

Columbia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.