How yeast cells communicate and form patterns
Official title: Cell-cell signaling and pattern formation in yeast
Funded at University of Missouri Kansas City · NIH-11043921 · Data updated 2026-11-12
This study looks at how yeast cells talk to each other to create organized groups, which could help us learn more about how similar communication works in human tissues, both healthy and unhealthy.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri Kansas City NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $469,500 |
| NIH project number | 1R15GM154311-01A1 |
| Project ID | NIH-11043921 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions related to cellular communication and signaling pathways.
✕Less likely to help
Patients with conditions unrelated to cellular communication or those not affected by signaling pathways may not receive any benefit from this research.
What this research studies
This research investigates how yeast cells communicate with each other to form organized patterns within their colonies. By studying the model organism Saccharomyces cerevisiae, the researchers aim to understand the role of secreted metabolites as signals that facilitate cell-to-cell communication. The project will utilize genetic techniques and observations of yeast colonies to explore the mechanisms behind this communication and its implications for both healthy and diseased tissues in humans.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cellular communication, potentially leading to new insights in treating diseases related to cell signaling.
How similar studies have gone: Previous research has shown success in understanding cellular communication in other microbial models, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Missouri Kansas City
Kansas City, United States Active
Researchers
- Principal investigator: Honigberg, Saul M — University of Missouri Kansas City
- Study coordinator: Honigberg, Saul M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.