How yeast cells adapt their signaling during cell division
Evolutionary adaptation and spatial organization of signaling in the Mitotic Exit Network
This study looks at how yeast cells communicate and adjust during their division process, focusing on a specific network that helps them switch between different stages, which could help us learn more about how cells work and potentially improve our understanding of cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11013378 on NIH RePORTER |
What this research studies
This research investigates how yeast cells use signaling pathways to adapt during different stages of cell division. By focusing on the Mitotic Exit Network (MEN), the study explores how this signaling cascade operates differently during mitosis and meiosis. The researchers will examine the mechanisms that activate key proteins involved in this process, aiming to understand how these adaptations occur in response to changes in cellular context. This could provide insights into fundamental cellular processes that may have implications for understanding cancer biology.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with cancers related to cell cycle dysregulation.
Not a fit: Patients with conditions unrelated to cell division or signaling pathways may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cell division, potentially leading to new strategies for targeting cancer cells.
How similar studies have performed: Other research has shown success in understanding signaling pathways in yeast, indicating that this approach has a foundation in established science.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Zhou, Xiaoxue — New York University
- Study coordinator: Zhou, Xiaoxue
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.