How work and unemployment affect dementia risk over a lifetime
Occupational transitions across the lifecourse and dementia risk: evaluating unemployment, occupational complexity using sequence analysis
This study is looking at how different work experiences, like changing jobs or being unemployed, might affect the chances of developing Alzheimer's and related dementias, so if you've ever wondered how your job could impact your brain health, this research is for you!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11082416 on NIH RePORTER |
What this research studies
This research investigates the relationship between work experiences, including job changes and unemployment, and the risk of developing Alzheimer's Disease and related dementias (ADRD) across a person's life. By analyzing data from large U.S. cohorts, the study aims to understand how different types of occupations and the demands they place on individuals can influence dementia risk. The researchers will create a detailed database that captures the physical, environmental, and cognitive aspects of various jobs to better assess their impact on brain health. This approach seeks to fill gaps in existing literature regarding the role of work in dementia risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults aged 65 and older who have experienced various work trajectories throughout their lives.
Not a fit: Patients who are younger than 65 or those who have not had significant work experiences may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing dementia by highlighting the importance of occupational experiences.
How similar studies have performed: Previous research has indicated that occupational factors can influence cognitive health, suggesting that this approach may yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Vable, Anusha Murthy — University of California, San Francisco
- Study coordinator: Vable, Anusha Murthy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.