How well flu and COVID-19 vaccines protect people in underserved Arizona communities

RFA-IP-22-004, Platform to Assess Influenza and COVID-19 Vaccine Effectiveness in Underserved Arizona Populations

['FUNDING_U01'] · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · NIH-11140260

This project looks at how well flu and COVID-19 vaccines protect people who get care in diverse, underserved areas of Phoenix, including people living with HIV.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorARIZONA STATE UNIVERSITY-TEMPE CAMPUS (nih funded)
Locations1 site (SCOTTSDALE, UNITED STATES)
Trial IDNIH-11140260 on ClinicalTrials.gov

What this research studies

From a patient's view, researchers will follow people who attend participating outpatient clinics to see who gets flu or COVID-19 and whether vaccination prevents sickness and hospital visits. They will combine medical records, symptom reports, and laboratory testing to identify infections and outcomes over time. The work focuses on a diverse and socioeconomically varied Phoenix population and includes people with weakened immune systems such as those with HIV. Data will help compare protection from seasonal flu vaccines, COVID-19 vaccines, and boosters during overlapping respiratory virus seasons.

Who could benefit from this research

Good fit: Ideal candidates are people who receive outpatient care at participating clinics in Phoenix/Maricopa County, especially those from underserved communities or with conditions like HIV that affect immune response.

Not a fit: People who live outside the Phoenix area or do not receive care at the participating clinics are unlikely to be enrolled or directly benefit from this project.

Why it matters

Potential benefit: If successful, this work could help tailor vaccine and booster recommendations for diverse and underserved Arizona communities to reduce infections and severe illness.

How similar studies have performed: Previous observational studies have measured flu or COVID-19 vaccine effectiveness separately, but combining both in a diverse, underserved Arizona population is relatively new.

Where this research is happening

SCOTTSDALE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.