How weight loss affects Alzheimer's disease risk in adults with Down syndrome
The Impact of Weight Loss on Alzheimer's Disease Risk in Adults with Down Syndrome
This study is looking at how losing weight through a special diet and support can help adults with Down syndrome lower their chances of developing Alzheimer's disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-11124489 on NIH RePORTER |
What this research studies
This research investigates the relationship between weight loss and the risk of developing Alzheimer's disease in adults with Down syndrome. It employs a multi-component intervention that includes a specially designed diet aimed at reducing caloric intake and improving dietary quality. Participants will receive individual counseling and support to help them achieve significant weight loss, which may in turn lower their risk of Alzheimer's disease. The study aims to provide insights into how dietary changes can impact health outcomes for this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with Down syndrome who are at risk for Alzheimer's disease and are willing to participate in a weight loss intervention.
Not a fit: Patients who do not have Down syndrome or who are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help reduce the risk of Alzheimer's disease in adults with Down syndrome through effective weight management.
How similar studies have performed: Previous research has shown that dietary interventions can be effective in reducing Alzheimer's disease risk in the general population, suggesting potential for success in this specific group.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Ptomey, Lauren Taylor — University of Kansas Medical Center
- Study coordinator: Ptomey, Lauren Taylor
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.