How vulnerability and resilience affect brain health as we age

EFFECTS OF VULNERABILITY AND RESILIENCY ON BRAIN HEALTH DURING THE MID-TO-LATE-LIFE TRANSITION

['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-10909106

This study is looking at how things like exercise, sleep, diet, and stress affect brain health for people aged 50 to 80, and it wants to find out what can help keep our minds sharp and lower the risk of Alzheimer's disease as we get older.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10909106 on ClinicalTrials.gov

What this research studies

This research investigates how factors like exercise, sleep, diet, and stress impact brain health during the transition from midlife to late life, specifically between the ages of 50 to 80. It aims to identify protective factors that can reduce the risk of cognitive decline and Alzheimer's disease. By examining these factors over time, the study seeks to understand when interventions may be most effective in promoting brain health. Participants will be monitored for changes in their cognitive function and overall health.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 50 to 80 who are concerned about their cognitive health or have risk factors for Alzheimer's disease.

Not a fit: Patients who are younger than 50 or those with advanced Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing cognitive decline and Alzheimer's disease in older adults.

How similar studies have performed: Previous research has shown promising results in identifying lifestyle factors that influence brain health, making this approach both relevant and potentially impactful.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.