How vitamin D affects calorie use in the body
Official title: Vitamin D control of calorie allocation to muscle
Funded at Children's Hosp of Philadelphia · NIH-11037895 · Data updated 2026-11-12
This study is looking at how vitamin D might help your body use extra calories for building muscle instead of storing them as fat, and it's for people who want to learn more about managing their weight and improving their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | February 15, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $458,947 |
| NIH project number | 5R01DK134717-03 |
| Project ID | NIH-11037895 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals struggling with obesity or related metabolic conditions who may benefit from new therapeutic approaches.
✕Less likely to help
Patients who are not overweight or do not have metabolic disorders may not receive benefit from this research.
What this research studies
This research investigates how vitamin D influences the way the body allocates calories, specifically focusing on redirecting excess calories from being stored as fat to being used for muscle growth. The study aims to understand the mechanisms behind this process, particularly through the action of vitamin D receptors. By exploring the effects of different vitamin D metabolites, the research seeks to develop new therapeutic strategies for obesity that could improve health outcomes and quality of life for patients. Participants may be involved in trials assessing dietary vitamin D's impact on calorie allocation.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for obesity that promote muscle growth instead of fat storage, potentially reducing the risk of related diseases.
How similar studies have gone: Other research has shown promising results in using vitamin D for metabolic health, suggesting that this approach may be viable.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Roizen, Jeffrey David — Children's Hosp of Philadelphia
- Study coordinator: Roizen, Jeffrey David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.