NIH-funded research Career grant

How vision problems affect dementia in stroke survivors

Official title: Influence of Vision Impairments on Dementia in Stroke Survivors: A Longitudinal Analysis

Funded at Duke University · NIH-11058379 · Data updated 2026-11-12

This study is looking at how vision problems might affect the chances of developing dementia in people who have had a stroke, and it aims to help improve care for those dealing with both vision and memory issues.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startApril 7, 2023
Project endApril 6, 2026
Funding year2025
Award (this year)$122,611
NIH project number5K01HD106010-03
Project IDNIH-11058379 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are stroke survivors who are also experiencing dementia and have vision impairments.

Less likely to help

Patients who have not experienced a stroke or do not have dementia or vision impairments may not benefit from this research.

What this research studies

This research investigates the relationship between vision impairments and dementia in individuals who have survived a stroke. By analyzing data from stroke survivors, the study aims to understand how specific types of vision issues may increase the risk of developing dementia. The research will involve comprehensive training in clinical assessment and research methodologies, allowing for a thorough examination of these interconnected health challenges. Patients may benefit from insights that could lead to improved care strategies for those experiencing both vision and cognitive impairments.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of dementia in stroke survivors with vision impairments.

How similar studies have gone: While there is limited research specifically linking vision impairments to dementia in stroke survivors, similar studies have shown promising results in understanding the broader impacts of sensory deficits on cognitive health.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Hreha, Kimberly Patrice — Duke University
  • Study coordinator: Hreha, Kimberly Patrice

Related research

Other NIH-funded projects on the same topics.

  • BBB Dysfunction after Stroke and Risk for Dementia

    A study at Stanford will look at whether inflammation after a stroke leads to leaky blood vessels and later dementia, by following stroke survivors and comparing them with people without stroke.

    NIH research Stanford University · Stanford, United States · NIH-11610460

  • DNMT3a and oligodendrocyte renewal after stroke

    A patient-focused study will explore how a specific gene, DNMT3a, might help repair brain white matter after a stroke to reduce dementia risk.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11462831

  • BBB Dysfunction after Stroke and Dementia Risk

    This NIH grant aims to understand why some people develop dementia years after a stroke by looking at brain inflammation and blood vessel leakage.

    NIH research Stanford University · Stanford, United States · NIH-11395559

  • Leaky brain blood vessels after stroke linked to dementia

    This work looks for MRI signs and blood markers of leaky blood vessels and inflammation in people who had a stroke years ago and may be at risk for memory and thinking problems.

    NIH research Stanford University · Stanford, United States · NIH-11395026

  • Understanding and reducing cognitive problems after stroke

    A study from the University of Michigan aims to see if simple cognitive activities and sleep improvements can lower the risk of developing vascular cognitive impairment and dementia after stroke.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11384379

  • Post-stroke cognitive decline and dementia: understanding and preventing PSCID

    A large NIH project will use real-world data from two million stroke records to better understand how many people develop PSCID and what factors raise that risk, with the goal of guiding prevention and care.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11382953

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.