How viruses move between wildlife and people in Uganda

Phylogenetic modeling of viral transmission dynamics at the human-wildlife interface in Uganda

NIH-funded research Washington University · NIH-11098622

Researchers will collect samples from red colobus monkeys and people who live near them in Uganda to find and track viruses that can jump between animals and people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11098622 on NIH RePORTER

What this research studies

If you live near Kibale National Park, the team will follow red colobus monkeys and people who neighbor the forest to learn where viruses spread. They will record monkey behavior in forest areas with different levels of human disturbance and interview local residents about how they interact with wildlife. The project will take repeat biological samples from individually identified monkeys and volunteer residents to sequence gut viruses and check for shared parasites. New evolutionary (phylodynamic) models will be used to map how detected viruses move and change between monkeys and people.

Who could benefit from this research

Good fit: Ideal participants are people living along the boundary of Kibale National Park in Uganda who have regular contact with the forest or wildlife and are willing to provide repeat biological samples and interview responses.

Not a fit: People who do not live near or interact with these wildlife populations or who cannot travel to the study area are unlikely to benefit directly from participation.

Why it matters

Potential benefit: This work could help detect emerging viruses earlier and guide actions to reduce the risk of viruses jumping from wildlife to people.

How similar studies have performed: Previous wildlife surveillance and genomic sequencing efforts have identified shared viruses and past spillovers, but applying new phylodynamic models specifically at the human–wildlife interface is relatively novel.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.