How vascular risk factors affect the risk of Alzheimer's disease after a stroke

The Effect of Vascular Risk Factors on Risk of Alzheimer's Disease and Related Dementias after Stroke (STROKE COG)

NIH-funded research University of Michigan at Ann Arbor · NIH-10875714

This study is looking at how things like high blood pressure, diabetes, and high cholesterol might affect the chances of stroke survivors developing Alzheimer's disease, so we can find better ways to help keep their brains healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10875714 on NIH RePORTER

What this research studies

This research investigates the relationship between vascular risk factors, such as high blood pressure, diabetes, and high cholesterol, and the risk of developing Alzheimer's disease and related dementias in stroke survivors. By understanding how these risk factors influence brain health post-stroke, the research aims to develop targeted interventions to reduce the incidence of Alzheimer's disease in this population. The study will analyze data from diverse groups of stroke survivors to inform clinical practices and public health policies. The ultimate goal is to create effective prevention strategies that can be implemented in healthcare settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a stroke and have vascular risk factors.

Not a fit: Patients who have not had a stroke or do not have any vascular risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new prevention strategies that significantly reduce the risk of Alzheimer's disease in stroke survivors.

How similar studies have performed: Previous research has shown promising results in understanding the impact of vascular risk factors on cognitive decline, suggesting that this approach could yield significant insights.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.