How vascular risk factors affect the risk of Alzheimer's disease after a stroke
Official title: The Effect of Vascular Risk Factors on Risk of Alzheimer's Disease and Related Dementias after Stroke (STROKE COG)
Funded at University of Michigan at Ann Arbor · NIH-10875714 · Data updated 2026-11-12
This study is looking at how things like high blood pressure, diabetes, and high cholesterol might affect the chances of stroke survivors developing Alzheimer's disease, so we can find better ways to help keep their brains healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 1, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $745,455 |
| NIH project number | 4R01AG068410-02 |
| Project ID | NIH-10875714 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced a stroke and have vascular risk factors.
✕Less likely to help
Patients who have not had a stroke or do not have any vascular risk factors may not benefit from this research.
What this research studies
This research investigates the relationship between vascular risk factors, such as high blood pressure, diabetes, and high cholesterol, and the risk of developing Alzheimer's disease and related dementias in stroke survivors. By understanding how these risk factors influence brain health post-stroke, the research aims to develop targeted interventions to reduce the incidence of Alzheimer's disease in this population. The study will analyze data from diverse groups of stroke survivors to inform clinical practices and public health policies. The ultimate goal is to create effective prevention strategies that can be implemented in healthcare settings.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies that significantly reduce the risk of Alzheimer's disease in stroke survivors.
How similar studies have gone: Previous research has shown promising results in understanding the impact of vascular risk factors on cognitive decline, suggesting that this approach could yield significant insights.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Levine, Deborah Allison — University of Michigan at Ann Arbor
- Study coordinator: Levine, Deborah Allison
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.