How vascular and metabolic disorders affect the risk of mild cognitive impairment and dementia
Official title: The predicative values of vascular and metabolic disorders for risk of incident mild cognitive impairment and dementia
Funded at Drexel University · NIH-10843813 · Data updated 2026-11-12
This study is looking at how heart and metabolic health can affect the chances of developing mild memory problems or Alzheimer's disease, and it hopes to find early signs that could help in spotting these issues sooner for better prevention.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | June 1, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $213,502 |
| NIH project number | 5R21AG082210-02 |
| Project ID | NIH-10843813 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults, particularly women, who may be at risk for mild cognitive impairment or dementia due to vascular or metabolic disorders.
✕Less likely to help
Patients who are younger than 21 or those without any vascular or metabolic disorders may not benefit from this research.
What this research studies
This research investigates the relationship between vascular and metabolic disorders and the risk of developing mild cognitive impairment (MCI) and dementia, particularly Alzheimer's disease. It aims to identify early indicators of MCI by analyzing various health factors over time. By understanding these associations, the research seeks to improve early detection and prevention strategies for cognitive decline. Patients may be monitored for changes in their health that could signal an increased risk of dementia.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and prevention strategies for mild cognitive impairment and dementia, improving patient outcomes.
How similar studies have gone: Previous research has shown associations between vascular and metabolic disorders and cognitive decline, but this study aims to fill gaps in large-scale population-based data, making it a novel approach.
Where this research is happening
-
Drexel University
Philadelphia, United States Active
Researchers
- Principal investigator: Liu, Longjian — Drexel University
- Study coordinator: Liu, Longjian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.