How vaping during pregnancy can affect a child's lung health
ENDS aerosol particle deposition, in utero exposures and children's respiratory health effects (ENDURE)
This project sees whether vaping or breathing in household e-cigarette (vape) aerosols during pregnancy changes babies' lung development and raises the chance of asthma in childhood.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project ID | NIH-11302679 on NIH RePORTER |
What this research studies
Researchers at three institutions will work together to follow pregnant people who use or are exposed to e-cigarettes and their children. They will measure how vape aerosol particles deposit in the mother's lungs, collect biological samples, and look for changes in inflammation-related genes in the offspring. The team will track children's breathing health over time, including signs of asthma and airway responsiveness. Lab analyses and clinical exams will be combined to link maternal exposures with child lung outcomes.
Who could benefit from this research
Good fit: Pregnant people who use e-cigarettes or live with household ENDS (vaping) exposure and their babies or young children would be the ideal participants.
Not a fit: People who were never exposed to e-cigarette aerosols during pregnancy or whose lung problems stem from clearly unrelated causes are unlikely to benefit directly from this research.
Why it matters
Potential benefit: If successful, this work could clarify how prenatal vaping affects childhood lung health and suggest ways to prevent or screen for asthma risk.
How similar studies have performed: Some animal studies and small human studies hint prenatal vaping can harm lung development, but large human studies linking maternal vape exposure to childhood asthma are limited, so this work addresses an important gap.
Where this research is happening
Bloomington, United States
- Trustees of Indiana University — Bloomington, United States (Active)
Researchers
- Principal investigator: Commodore, Sarah — Trustees of Indiana University
- Study coordinator: Commodore, Sarah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.