How vaginal bacteria affect the risk of Chlamydia infections
Impact of the vaginal microbiome on Chlamydia trachomatis acquisition
This study is looking at how the bacteria in the vagina might affect a woman's chances of getting a Chlamydia infection, and it's for women who want to understand more about their health and how their body's bacteria can play a role in preventing infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10541862 on NIH RePORTER |
What this research studies
This research investigates the relationship between the vaginal microbiome and the risk of acquiring Chlamydia trachomatis infections. By analyzing samples from women in the Mombasa Cohort study, the research aims to identify specific bacterial species and their metabolites that may influence susceptibility to this common sexually transmitted infection. The study employs a combination of epidemiological methods and laboratory analyses, including PCR techniques, to assess the presence and concentration of these bacteria and their potential impact on infection risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who are at risk of Chlamydia trachomatis infections and are participating in the Mombasa Cohort study.
Not a fit: Patients who are not women or those who are not at risk for Chlamydia infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies for Chlamydia infections, potentially reducing their incidence.
How similar studies have performed: Previous studies have shown associations between bacterial vaginosis and increased risk of Chlamydia, but this research aims to explore these relationships in greater depth, making it a novel approach.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Mcclelland, Raymond Scott — University of Washington
- Study coordinator: Mcclelland, Raymond Scott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.