How vaccines affect heart health and inflammation
Official title: Vaccine Induced Immune-Inflammatory Response and Cardiovascular Risk
Funded at Cedars-Sinai Medical Center · NIH-10815560 · Data updated 2026-11-12
This study is looking at how vaccines might affect heart health in people who already have heart problems, by checking how their immune systems respond to the vaccines and if that changes their risk of heart issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | April 1, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $718,171 |
| NIH project number | 5R01HL151828-04 |
| Project ID | NIH-10815560 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old, particularly those with existing cardiovascular conditions.
✕Less likely to help
Patients without cardiovascular disease or those who are not receiving vaccinations may not benefit from this research.
What this research studies
This research investigates the relationship between vaccine-induced immune responses and cardiovascular risk, particularly focusing on how vaccinations can influence heart health in individuals with cardiovascular disease. It aims to understand the variability in immune responses to vaccines and how these responses can affect the risk of cardiovascular events. By examining the role of immune-inflammatory pathways and specific molecular mediators, the research seeks to identify factors that enhance the protective effects of vaccinations against heart-related issues. Patients may be monitored for their immune responses and cardiovascular health outcomes following vaccination.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that better protect individuals with cardiovascular disease from serious health complications.
How similar studies have gone: Previous research has shown promising results in understanding the immune response to vaccinations, but this specific focus on cardiovascular risk is relatively novel.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Cheng, Susan — Cedars-Sinai Medical Center
- Study coordinator: Cheng, Susan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.