How urban stressors affect mental health in children

Effects of Urban Chemical and Non-Chemical Stressors on Preadolescent Mental Health

['FUNDING_OTHER'] · UNIVERSITY OF CHICAGO · NIH-11082252

This study is looking at how things like air pollution, noise, and violence in cities affect the mental health of kids and teens, especially how they might lead to feelings of anxiety and depression, so we can better understand what’s happening and help those who are struggling.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CHICAGO (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-11082252 on ClinicalTrials.gov

What this research studies

This research investigates the impact of urban environmental stressors, such as air pollution and non-chemical factors like noise and violence, on the mental health of children and adolescents. It aims to understand how these stressors contribute to anxiety and depression in preadolescents, particularly in urban settings where these issues are more prevalent. The study will explore the biological mechanisms involved, particularly focusing on the role of cortisol and the hypothalamic-pituitary-adrenal (HPA) axis in mediating these effects. By analyzing data from children exposed to various urban stressors, the research seeks to uncover critical insights into the origins of mental health disorders in youth.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 9 to 11 years who live in urban areas and may be experiencing symptoms of anxiety or depression.

Not a fit: Patients who are not within the age range of 9 to 11 years or those living in rural areas may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for anxiety and depression in children living in urban environments.

How similar studies have performed: Previous research has shown that environmental factors significantly impact mental health, but this specific focus on urban stressors in children is relatively novel.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.