How unhealthy fat tissue affects liver disease and diabetes
Dysfunctional adipose tissue's role in hepatic metabolic disease
['FUNDING_OTHER'] · UNIVERSITY OF KANSAS MEDICAL CENTER · NIH-11044229
This study is looking at how unhealthy fat in our bodies can lead to fatty liver disease and type 2 diabetes, and it aims to find ways to help people improve their metabolic health by understanding how fat works in our bodies.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KANSAS MEDICAL CENTER (nih funded) |
| Locations | 1 site (KANSAS CITY, UNITED STATES) |
| Trial ID | NIH-11044229 on ClinicalTrials.gov |
What this research studies
This research investigates the role of dysfunctional adipose tissue in the development of fatty liver disease and type 2 diabetes. It focuses on understanding how the function of fat tissue, rather than just its amount, influences metabolic health. The study will explore the mechanisms by which unhealthy fat storage and release of fatty acids impact liver metabolism and contribute to disease. By examining these processes, the research aims to identify potential targets for improving metabolic health in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing obesity or related metabolic disorders.
Not a fit: Patients with healthy adipose tissue function or those without metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve metabolic health and reduce the risk of fatty liver disease and diabetes.
How similar studies have performed: Other research has shown promising results in understanding the relationship between adipose tissue function and metabolic diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
KANSAS CITY, UNITED STATES
- UNIVERSITY OF KANSAS MEDICAL CENTER — KANSAS CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUTKEWITTE, ANDREW — UNIVERSITY OF KANSAS MEDICAL CENTER
- Study coordinator: LUTKEWITTE, ANDREW
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.