How unexpected events can improve memory and learning
The role of novelty and surprise in aversive conditioning
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10881909
This study is looking at how surprising and new experiences can help us learn and remember better, and it might lead to new ways to support people with memory issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10881909 on ClinicalTrials.gov |
What this research studies
This research investigates how novelty and surprise can enhance learning and memory processes. It explores the mechanisms by which unexpected events trigger the release of important neurotransmitters, norepinephrine and dopamine, which are crucial for forming new memories. By examining both human and animal responses to surprising stimuli, the study aims to understand how these experiences can be harnessed to improve memory retention. Patients may benefit from insights that could lead to new therapeutic strategies for memory-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing memory issues related to conditions such as Alzheimer's disease or ADHD.
Not a fit: Patients with stable cognitive function and no memory-related concerns may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative approaches for improving memory in patients with cognitive impairments.
How similar studies have performed: Previous research has shown that novelty and surprise can enhance memory, suggesting that this approach has potential for meaningful advancements.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILTGEN, BRIAN J — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: WILTGEN, BRIAN J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease