How undernutrition affects immune development in Bangladeshi children
Official title: Undernutrition, microbiota maturation, and adaptive immunity in Bangladeshi children
Funded at University of Vermont & St Agric College · NIH-10931512 · Data updated 2026-11-12
This study is looking at how not getting enough nutrition affects the immune system and gut health in children in Bangladesh, so we can better understand how to help them grow stronger and fight off infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Vermont & St Agric College NIH-funded |
| Lab location | 1 site (Burlington, United States) |
| Project start | September 18, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $519,117 |
| NIH project number | 5R01HD112491-02 |
| Project ID | NIH-10931512 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children under the age of 5 who are experiencing undernutrition in Bangladesh.
✕Less likely to help
Children who are well-nourished or those outside the age range of 0-5 years may not benefit from this research.
What this research studies
This research investigates the impact of undernutrition on the immune system and gut microbiota in children from Bangladesh. By following a group of children over time, the study aims to understand how undernutrition affects their growth and susceptibility to infections. Researchers will use advanced techniques, such as stool metagenomic sequencing, to analyze the gut microbiota and its role in immune development. The findings could help identify critical periods for intervention to improve health outcomes in undernourished children.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing infections and enhancing growth in undernourished children.
How similar studies have gone: Previous research has shown that understanding the relationship between nutrition and immune development can lead to significant health improvements, suggesting this approach has potential for success.
Where this research is happening
-
University of Vermont & St Agric College
Burlington, United States Active
Researchers
- Principal investigator: Lee, Benjamin — University of Vermont & St Agric College
- Study coordinator: Lee, Benjamin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.