How ultrasound affects blood sugar control and diabetes
Official title: Mechanism of ultrasound neuromodulation effects on glucose homeostasis and diabetes
Funded at Yale University · NIH-11018634 · Data updated 2026-11-12
This study is looking at how using gentle ultrasound on the brain might help improve blood sugar control for people with diabetes by changing how the brain and gut communicate about glucose levels.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $754,027 |
| NIH project number | 5R01DK131127-03 |
| Project ID | NIH-11018634 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with adult-onset diabetes who are seeking alternative treatment options.
✕Less likely to help
Patients with type 1 diabetes or those who do not have issues with glucose regulation may not benefit from this research.
What this research studies
This research investigates the role of the central nervous system in regulating glucose metabolism, particularly focusing on how ultrasound neuromodulation can influence autonomic pathways that communicate between the gastrointestinal tract and the brain. By using non-invasive ultrasound techniques, the study aims to alter the brain's response to glucose levels, potentially leading to improved blood sugar control. The research builds on promising animal studies that have shown ultrasound can normalize glucose levels without insulin. The goal is to translate these findings into human applications to better manage diabetes.
Why it matters
Potential benefit: If successful, this research could provide a novel, non-invasive treatment option for managing blood sugar levels in diabetes patients.
How similar studies have gone: Preliminary studies in animal models have shown success with similar ultrasound neuromodulation approaches, indicating potential for human application.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Herzog, Raimund Ingo — Yale University
- Study coordinator: Herzog, Raimund Ingo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.