How ultrasound affects blood sugar control and diabetes
Mechanism of ultrasound neuromodulation effects on glucose homeostasis and diabetes
This study is looking at how using gentle ultrasound on the brain might help improve blood sugar control for people with diabetes by changing how the brain and gut communicate about glucose levels.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11018634 on NIH RePORTER |
What this research studies
This research investigates the role of the central nervous system in regulating glucose metabolism, particularly focusing on how ultrasound neuromodulation can influence autonomic pathways that communicate between the gastrointestinal tract and the brain. By using non-invasive ultrasound techniques, the study aims to alter the brain's response to glucose levels, potentially leading to improved blood sugar control. The research builds on promising animal studies that have shown ultrasound can normalize glucose levels without insulin. The goal is to translate these findings into human applications to better manage diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with adult-onset diabetes who are seeking alternative treatment options.
Not a fit: Patients with type 1 diabetes or those who do not have issues with glucose regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a novel, non-invasive treatment option for managing blood sugar levels in diabetes patients.
How similar studies have performed: Preliminary studies in animal models have shown success with similar ultrasound neuromodulation approaches, indicating potential for human application.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Herzog, Raimund Ingo — Yale University
- Study coordinator: Herzog, Raimund Ingo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.