How type 1 diabetes affects brain development and cognitive abilities

Diabetes Brain and Cognitive Development-Type 1 (DBCD-T1)

NIH-funded research University of Florida · NIH-10973722

This study looks at how type 1 diabetes affects brain development and thinking skills in kids and older adults, exploring how changes in blood sugar levels might influence brain health and mental abilities, so we can better understand the risks of cognitive challenges for people with diabetes.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-10973722 on NIH RePORTER

What this research studies

This research investigates the impact of type 1 diabetes on brain development and cognitive functioning across different age groups. It focuses on how fluctuations in glucose levels can lead to changes in brain structure and cognitive abilities, particularly in children and older adults. By utilizing neuroimaging techniques, the study aims to identify the relationship between diabetes management and cognitive outcomes, helping to understand the risks associated with cognitive impairment in individuals with type 1 diabetes.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with type 1 diabetes, particularly those experiencing cognitive challenges or those at risk for cognitive decline.

Not a fit: Patients without a diagnosis of type 1 diabetes or those who do not experience cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing type 1 diabetes that enhance cognitive health and brain development.

How similar studies have performed: Previous research has shown that managing glucose levels can positively influence cognitive outcomes in individuals with diabetes, suggesting that this approach may yield beneficial results.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.