How tumors affect blood cell production in the body
Official title: Regulation of hematopoiesis during tumor progression
Funded at Washington University · NIH-10948087 · Data updated 2026-11-12
This study is looking at how tumors affect blood cell production in the bone marrow and how certain cells can weaken the immune system's fight against cancer, with the goal of finding new ways to help cancer patients boost their immune response.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 5F31CA284858-02 |
| Project ID | NIH-10948087 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients diagnosed with various types of cancer who are experiencing changes in their immune response.
✕Less likely to help
Patients with non-cancerous conditions or those whose tumors are not affecting their immune system may not benefit from this research.
What this research studies
This research investigates how tumors influence the production of blood cells in the bone marrow, particularly focusing on the immune system's response to cancer. It examines the role of immature myeloid cells, which can suppress the immune response against tumors, and how these cells change during tumor progression. By understanding the mechanisms involved, the research aims to identify potential targets for improving immune responses in cancer patients. Patients may benefit from insights that could lead to new treatments enhancing their immune system's ability to fight tumors.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance the immune system's ability to combat tumors, potentially improving survival rates for cancer patients.
How similar studies have gone: Previous research has shown that targeting immune suppressive mechanisms can improve cancer treatment outcomes, suggesting that this approach may also yield beneficial results.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Eul, Emily M — Washington University
- Study coordinator: Eul, Emily M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.