How triglycerides in pregnant women affect fat in newborns
Official title: Triglycerides as a Predictor of Newborn Subcutaneous and Liver Fat: Contributors to Fetal Fat Accretion in Obese Pregnancies
Funded at University of Colorado Denver · NIH-11083158 · Data updated 2026-11-12
This study is looking at how the fat levels in newborns might be influenced by the triglyceride levels in their mothers during pregnancy, especially for babies born to moms who are obese, to help understand potential health risks for the little ones later on.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | May 7, 2021 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $641,248 |
| NIH project number | 5R01HD102726-04 |
| Project ID | NIH-11083158 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant women who are classified as overweight or obese.
✕Less likely to help
Patients who are not pregnant or those with normal weight may not benefit from this research.
What this research studies
This research investigates the relationship between maternal triglyceride levels and the amount of fat in newborns, particularly focusing on infants born to obese mothers. It aims to understand how elevated triglycerides during pregnancy can predict increased fat accumulation in newborns, which is linked to future metabolic diseases. The study utilizes data from previous trials and examines the impact of maternal obesity and gestational diabetes on newborn fat levels. By analyzing triglyceride levels at different stages of pregnancy, the research seeks to identify potential early indicators of fat accumulation in infants.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing pregnancies in obese women, potentially reducing the risk of obesity and metabolic diseases in their children.
How similar studies have gone: Previous research has indicated a correlation between maternal obesity and increased fat in newborns, suggesting that this approach has been explored but may still offer novel insights.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Barbour, Linda Anne — University of Colorado Denver
- Study coordinator: Barbour, Linda Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.