How triclosan exposure affects hormones and gut bacteria in adolescents and its impact on behavior.
Official title: Triclosan, pubertal hormones, and the gut microbiome: implications for neurobehavior
Funded at University of Massachusetts Amherst · NIH-11142696 · Data updated 2026-11-12
This study is looking at how exposure to triclosan, a common antibacterial ingredient, might change the gut bacteria and hormones in teenagers, which could affect their behavior, and it involves collecting stool samples from adolescents to see how these factors are connected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Amherst NIH-funded |
| Lab location | 1 site (Hadley, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $248,958 |
| NIH project number | 4R00ES034086-03 |
| Project ID | NIH-11142696 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adolescents aged 12 to 20 who have been exposed to triclosan and may experience neurobehavioral challenges.
✕Less likely to help
Patients outside the age range of 12 to 20 or those not exposed to triclosan may not benefit from this research.
What this research studies
This research investigates how exposure to triclosan, a common antimicrobial agent, influences the gut microbiome and hormonal changes during adolescence, which may affect behavior. By analyzing data from a longitudinal study, the researchers will examine the relationship between triclosan exposure, pubertal hormones, and the composition of gut bacteria in adolescents. Participants will provide stool samples, which will be analyzed to understand how these factors interact and potentially lead to neurobehavioral changes. The study aims to identify critical periods during adolescence when these influences are most pronounced.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of neurobehavioral issues in adolescents, particularly those related to ADHD and anxiety.
How similar studies have gone: While some studies have explored the microbiome in infants and adults, this research is novel as it focuses specifically on the adolescent microbiome and its relationship with environmental exposures.
Where this research is happening
-
University of Massachusetts Amherst
Hadley, United States Active
Researchers
- Principal investigator: Laue, Hannah Elizabeth — University of Massachusetts Amherst
- Study coordinator: Laue, Hannah Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.