How traumatic stress affects brain myelination
Individual Variation in Effects of Traumatic Stress on Gray Matter Myelin
This study is looking at how experiencing trauma in early adulthood affects the brain's protective covering and how that might make people more sensitive to stress, especially for those dealing with PTSD symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northern California Institute/res/edu NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10516079 on NIH RePORTER |
What this research studies
This research investigates how traumatic stress impacts the myelination of gray matter in the brain, particularly focusing on individuals who have experienced trauma during early adulthood. The study aims to understand the mechanisms that lead to heightened sensitivity to threats, which can manifest as symptoms of PTSD. By utilizing advanced brain imaging techniques, researchers will analyze changes in myelin content and its correlation with trauma-related symptoms. The findings could reveal how environmental stressors influence brain structure and function, potentially leading to new therapeutic approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced traumatic stress and exhibit symptoms of PTSD.
Not a fit: Patients who have not experienced trauma or do not exhibit symptoms related to traumatic stress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals suffering from PTSD and related conditions.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between myelination and trauma, indicating that this approach could yield significant insights.
Where this research is happening
San Francisco, United States
- Northern California Institute/res/edu — San Francisco, United States (Active)
Researchers
- Principal investigator: Neylan, Thomas C — Northern California Institute/res/edu
- Study coordinator: Neylan, Thomas C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.