How traumatic brain injury during pregnancy affects the brain development of children
Gravida traumatic brain injury (TBI) impacts neurodevelopment of the offspring
['FUNDING_R01'] · UNIVERSITY OF ARIZONA · NIH-11178187
This study looks at how traumatic brain injuries from domestic violence during pregnancy might affect the brain development of babies, helping us understand the risks involved for both moms and their children.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-11178187 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of traumatic brain injury (TBI) experienced by pregnant women due to intimate partner violence on the neurodevelopment of their offspring. It aims to understand how such injuries can lead to stress and inflammation that may disrupt fetal brain development. The study will utilize laboratory experiments to explore the effects of gTBI on neuropsychiatric outcomes and neural circuit changes in offspring. By establishing a link between maternal TBI and developmental disorders, the research seeks to highlight gTBI as a significant environmental risk factor.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women who have experienced intimate partner violence and may have sustained a traumatic brain injury.
Not a fit: Patients who have not experienced intimate partner violence or traumatic brain injury during pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for developmental disorders in children born to mothers who have experienced TBI during pregnancy.
How similar studies have performed: While the specific focus on gTBI during pregnancy is novel, related research has shown that maternal health impacts child neurodevelopment, indicating potential for significant findings.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIFSHITZ, JONATHAN — UNIVERSITY OF ARIZONA
- Study coordinator: LIFSHITZ, JONATHAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.