How touch sensations in the tongue affect flavor perception

Mechanosensory substrates of flavor in the mammalian tongue

NIH-funded research New York University · NIH-10744208

This study is looking at how certain nerve cells in the tongue help us taste flavors by sensing food textures, which could help us understand how what we eat affects our taste and food choices.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionNew York University NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10744208 on NIH RePORTER

What this research studies

This research investigates the role of mechanosensory neurons in the tongue and how they influence flavor perception. By using advanced techniques such as mouse transgenic technology and in vivo calcium imaging, the study aims to identify the types of mechanosensory neurons present in the tongue and the ion channels involved in their function. Understanding these mechanisms could provide insights into how food texture and touch sensations impact our taste experiences and dietary choices.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in how sensory experiences affect their food preferences and eating behaviors.

Not a fit: Patients with no interest in flavor perception or those who do not consume solid foods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of flavor perception, potentially influencing dietary habits and nutritional intake.

How similar studies have performed: While the investigation of mechanosensory neurons is a relatively novel approach, previous studies have shown promising results in understanding sensory integration in other contexts.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.