How tiny vesicles help heal wounds
Official title: Mechanisms of extracellular vesicle biogenesis that regulate wound healing
Funded at University of California, San Diego · NIH-10909004 · Data updated 2026-11-12
This study is looking at how tiny particles called extracellular vesicles help cells talk to each other during wound healing, and it aims to find ways to boost their healing abilities to help people who have trouble healing wounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $410,800 |
| NIH project number | 5R35GM149245-02 |
| Project ID | NIH-10909004 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with chronic wounds or conditions that impair normal healing processes.
✕Less likely to help
Patients with acute wounds that heal normally without complications may not benefit from this research.
What this research studies
This research investigates the role of extracellular vesicles (EVs) in wound healing, focusing on how these tiny particles facilitate communication between cells during tissue repair. By using genetic tools, the researchers aim to modify the production and content of EVs to enhance their healing properties. The study will explore how different types of EVs interact with immune and epithelial cells in the wound area, potentially leading to improved therapies for patients with impaired wound healing.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve wound healing for patients with chronic injuries.
How similar studies have gone: Previous research has shown promise in using extracellular vesicles for tissue repair, indicating that this approach could be effective.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Eliceiri, Brian P — University of California, San Diego
- Study coordinator: Eliceiri, Brian P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.