How tiny vesicles help cells communicate during embryo implantation
Extracellular vesicles as mediators of cell-cell communication during implantation
['FUNDING_R21'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-10684030
This study is looking at tiny particles released by cells in the uterus to see how they help with the important process of embryo implantation, which could lead to better understanding and support for healthy pregnancies.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-10684030 on ClinicalTrials.gov |
What this research studies
This research investigates the role of extracellular vesicles (EVs) in cell communication during the critical process of embryo implantation. It focuses on how these vesicles, which carry important biological signals, are secreted by decidual cells in the uterus and how they influence the development of blood vessels and the placenta. By analyzing the contents of these vesicles, the research aims to uncover the mechanisms that support successful pregnancy establishment. Patients may benefit from insights gained into the factors that promote healthy implantation and fetal development.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing difficulties with implantation or early pregnancy complications.
Not a fit: Patients who are not currently pregnant or not planning to conceive may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatments for implantation-related issues in pregnancy.
How similar studies have performed: Other research has shown promising results regarding the role of extracellular vesicles in various physiological processes, suggesting potential for success in this area as well.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAGCHI, INDRANI C — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: BAGCHI, INDRANI C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.