How tiny involuntary eye movements help vision

Function of Fixational Instability During Natural Viewing

NIH-funded research University of Rochester · NIH-11166503

This project looks at how small, constant eye movements influence depth perception and 3-D vision in people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11166503 on NIH RePORTER

What this research studies

From your point of view, researchers will record natural, tiny eye movements while you look at images and 3-D scenes to see how each eye’s small jitters affect what you perceive. The team will run behavioral tests of stereopsis (depth perception), use precise eye-tracking to compare the two eyes, and combine those data with computational models of how the brain decodes binocular input. Some experiments probe the control of those movements to learn how the eyes are coordinated, and others examine how the changing inputs shape perception. Participation mainly involves lab visits for vision tasks and eye-movement recordings.

Who could benefit from this research

Good fit: Ideal participants are adults willing to undergo vision tests and eye-tracking, including people with typical binocular vision and those with binocular vision differences such as stereo deficits or strabismus.

Not a fit: People whose health problems are unrelated to vision, or who cannot reliably sit still for eye-tracking or follow visual task instructions, are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, this work could improve understanding of how binocular eye movements shape depth perception and help develop better diagnostics or treatments for binocular vision problems.

How similar studies have performed: Previous research shows fixational eye movements matter for single-eye acuity, but applying these ideas to binocular depth perception and control is a newer direction.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.