How the vagus nerve senses inflammation in the body
Encoding of inflammatory mediators by vagal sensory neurons
This study is looking at how the vagus nerve helps the body sense inflammation, which could lead to new treatments for people with inflammatory conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10884202 on NIH RePORTER |
What this research studies
This research investigates the communication between the nervous system and the immune system, focusing on how the vagus nerve detects inflammation. By using advanced imaging techniques, the study aims to understand how vagal sensory neurons respond to various inflammatory signals. Patients may benefit from insights gained about the mechanisms of inflammation, which could lead to new treatments for inflammatory conditions. The research seeks to uncover the neural codes that represent these immune signals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from conditions characterized by inflammation, such as autoimmune diseases or chronic inflammatory disorders.
Not a fit: Patients with non-inflammatory conditions or those not affected by immune system dysregulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing inflammatory diseases.
How similar studies have performed: Previous research has shown promising results in understanding neuro-immune interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Chang, Eric Hau-Yun — Feinstein Institute for Medical Research
- Study coordinator: Chang, Eric Hau-Yun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.