How the timing of salt intake affects blood pressure in obese African Americans

Timing of sodium intake and nocturnal sodium excretion and blood pressure in obese African Americans

NIH-funded research University of Alabama at Birmingham · NIH-10649700

This study is looking at how when you eat salt affects blood pressure and how your body gets rid of sodium, specifically for obese African American adults, to see if cutting back on salt before bedtime can help keep blood pressure in check.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10649700 on NIH RePORTER

What this research studies

This research investigates how the timing of sodium intake influences blood pressure and sodium excretion patterns in obese African American adults. It aims to understand the relationship between high salt consumption, nocturnal hypertension, and circadian rhythms. Participants will be involved in a randomized, cross-over feeding study to assess how limiting salt intake before sleep can improve blood pressure regulation. The study focuses on the unique physiological responses of this population to dietary sodium.

Who could benefit from this research

Good fit: Ideal candidates for this research are obese African American adults who experience non-dipping sleep blood pressure patterns.

Not a fit: Patients who are not obese or do not have issues with blood pressure regulation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved dietary recommendations that help manage blood pressure and reduce health risks for obese African Americans.

How similar studies have performed: Previous research has shown promising results regarding the impact of dietary sodium timing on blood pressure, indicating that this approach may be effective.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.