NIH-funded research NIH-funded research

How the timing of physical activity affects heart and metabolic health

Official title: Timing of Physical Activity on Cardiometabolic Health Outcomes

Funded at Brigham and Women's Hospital · NIH-10897126 · Data updated 2026-11-12

This study is looking at how the time of day you exercise might affect your heart health and diabetes management, and it's for people with type 2 diabetes who want to find out the best times to work out for better health.

More Cardiometabolic Health research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2026
Funding year2024
Award (this year)$248,939
NIH project number5R00HL148500-04
Project IDNIH-10897126 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults diagnosed with type 2 diabetes who engage in or are willing to engage in physical activity.

Less likely to help

Patients who do not have type 2 diabetes or those who are unable to participate in physical activity may not benefit from this research.

What this research studies

This research investigates how the timing of physical activity influences health outcomes related to cardiovascular diseases and type 2 diabetes. By analyzing data from a large clinical trial involving approximately 2,200 patients with type 2 diabetes, the study aims to determine if exercising at different times of the day leads to varying health benefits. The approach includes using accelerometers to track physical activity and examining its relationship with metabolic responses influenced by the body's circadian rhythms. This could help identify optimal times for exercise to maximize health improvements.

Why it matters

Potential benefit: If successful, this research could lead to personalized exercise recommendations that enhance health outcomes for individuals at risk of cardiovascular diseases and diabetes.

How similar studies have gone: Previous animal studies have shown promising results regarding the effects of exercise timing on metabolic health, suggesting potential for success in human applications.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Qian, Jingyi — Brigham and Women's Hospital
  • Study coordinator: Qian, Jingyi

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.