NIH-funded research R01 grant

How the timing of food intake affects reproductive health

Official title: The circadian time of food intake and its effect on reproductive health

Funded at Oregon Health & Science University · NIH-11061826 · Data updated 2026-11-12

This study looks at how eating at odd times can mess with your body's internal clock and affect fertility, especially for people with irregular eating habits like shift workers, and it aims to understand how these timing issues can disrupt hormones that are important for reproduction.

More Reproductive Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startMay 15, 2023
Project endMarch 31, 2028
Funding year2025
Award (this year)$567,985
NIH project number5R01HD109477-03
Project IDNIH-11061826 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing reproductive health issues, particularly those with irregular eating patterns or shift work schedules.

Less likely to help

Patients who have stable eating patterns and do not experience reproductive health issues may not benefit from this research.

What this research studies

This research investigates how disruptions in the body's internal clock, particularly related to food intake timing, impact reproductive health. It focuses on understanding the mechanisms behind reduced fertility and other reproductive issues observed in individuals with irregular eating patterns, such as shift workers. By using animal models, the study aims to explore how mis-timed meals can lead to hormonal disruptions that affect ovulation and mating behaviors. The research will assess the sensitivity of both male and female reproductive functions to these dietary timing changes.

Why it matters

Potential benefit: If successful, this research could lead to new dietary guidelines that improve reproductive health and fertility outcomes.

How similar studies have gone: Previous research has indicated that circadian disruptions can negatively affect reproductive health, suggesting that this approach has a foundation in existing findings.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Butler, Matthew P — Oregon Health & Science University
  • Study coordinator: Butler, Matthew P

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.