NIH-funded research R01 grant

How the thalamus helps attention and what we see

Official title: Functions of the thalamus in attention and perception

Funded at Princeton University · NIH-11394584 · Data updated 2026-11-12

This work looks at how a deep brain area called the pulvinar helps the brain focus attention and process visual information, with relevance for people with attention or autism-related challenges.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPrinceton University
NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project startApril 1, 2007
Project endMarch 31, 2029
Funding year2026
Award (this year)$574,574
NIH project number5R01EY017699-15
Project IDNIH-11394584 on NIH RePORTER

Who could benefit from this research

Could help

This grant primarily funds basic neuroscience in animal models and does not currently enroll patients, though people with ADHD or autism might be eligible for related human studies if they are offered in the future.

Less likely to help

People looking for immediate clinical treatment or therapy will not directly benefit from this basic, animal-focused research in the short term.

What this research studies

Researchers record brain signals from the pulvinar and connected cortical areas while primates perform attention and vision tasks to map how these areas coordinate. They combine simultaneous multi-site electrical recordings with knowledge from human and monkey lesion studies to link neural activity patterns to attention behavior. The team examines connections between the pulvinar, frontal and parietal cortex, and the superior colliculus to see how information is routed and filtered during attention. Findings aim to clarify the circuits that allow the brain to ignore distractions and select important visual information.

Why it matters

Potential benefit: A clearer map of attention circuits could eventually lead to new diagnostics or therapies for attention difficulties in ADHD or autism.

How similar studies have gone: Previous lesion and recording studies in humans and monkeys have suggested a role for the pulvinar in attention, and this project builds on promising but still early evidence.

Where this research is happening

  • Princeton University
    Princeton, United States
    Active

Researchers

  • Principal investigator: Kastner, Sabine — Princeton University
  • Study coordinator: Kastner, Sabine

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.