How the subtalar joint changes after ankle fusion for varus ankle osteoarthritis

Morphologic and Kinematic Adaptations of the Subtalar Joint after Ankle Fusion Surgery in Patients with Varus-type Ankle Osteoarthritis

NIH-funded research Utah State Higher Education System--University of Utah · NIH-11146504

This project looks at how the subtalar joint's shape and movement change after ankle fusion in people with varus-type ankle osteoarthritis.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUtah State Higher Education System--University of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11146504 on NIH RePORTER

What this research studies

If you have varus-type ankle osteoarthritis and are considering tibiotalar arthrodesis (ankle fusion), researchers will use 3-D imaging and motion analysis to measure how your subtalar joint's shape and movement change before and after surgery. They will compare patients who have a compensatory valgus alignment of the subtalar joint with those who do not, using CT scans and kinematic gait testing. The team builds on earlier pilot data and will analyze alignment, joint space, and motion to see how surgical alignment choices affect subtalar mechanics over time. Results are intended to guide surgeons toward fusion positions that reduce abnormal loading and the risk of secondary subtalar arthritis.

Who could benefit from this research

Good fit: Ideal candidates are adults with varus-type ankle osteoarthritis who are scheduled for tibiotalar arthrodesis and can attend pre- and postoperative imaging and gait visits.

Not a fit: Patients without varus deformity, those not undergoing ankle fusion, or those with prior subtalar fusion or unrelated foot conditions are unlikely to benefit from this specific research.

Why it matters

Potential benefit: If successful, the work could help surgeons position ankle fusions to protect the subtalar joint and lower the chance of later arthritis and disability.

How similar studies have performed: Previous smaller studies and the investigators' own R21 showed promising signs that surgical alignment affects subtalar mechanics, but larger confirmatory data are still needed.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.