How the oral microbiome affects inflammation in people with HIV
Role of the oral microbiome in driving local and systemic inflammation in HIV
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10894809
This study is looking at how bacteria in the mouth might affect inflammation in people with HIV, and it hopes to find ways to improve health by understanding the connection between oral and gut bacteria.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10894809 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the oral microbiome in contributing to inflammation in individuals living with HIV. It aims to understand how bacteria from the mouth may travel to the gut and influence systemic inflammation, which can lead to various health complications. By examining the connections between oral and gut bacteria, the study seeks to uncover mechanisms that could help reduce inflammation and improve health outcomes for HIV patients. The research will involve analyzing microbiome samples and assessing their impact on inflammation-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are experiencing chronic inflammation or related health complications.
Not a fit: Patients who are not living with HIV or those without any signs of inflammation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing inflammation and associated health issues in HIV patients.
How similar studies have performed: While research on the oral microbiome in general is growing, studies specifically linking it to HIV-related inflammation are limited, making this approach relatively novel.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FULCHER, JENNIFER — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: FULCHER, JENNIFER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus