How the infant gut microbiome affects asthma development
Divergent Functional and Metabolic Development of the Infant Microbiome
This study is looking at how the gut bacteria of babies in Nogales, Mexico, and Tucson, Arizona, might affect their chances of developing asthma, by examining stool samples from mothers and their infants to see how different bacteria could influence their immune health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10932534 on NIH RePORTER |
What this research studies
This research investigates the differences in the gut microbiome of infants from two populations: one in Nogales, Mexico, and another in Tucson, Arizona. It aims to understand how early life environmental exposures and the composition of the microbiome influence asthma rates in children. By analyzing stool samples from mother-infant pairs, the study will explore the relationship between microbial diversity and asthma outcomes. The research will focus on identifying specific bacterial genera that may play a role in immune function and asthma susceptibility.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants aged 0-4 weeks from Mexican or Mexican-American families living in Nogales or Tucson.
Not a fit: Patients who are older than 2 years or do not have a family history of asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing asthma in children by understanding the role of the microbiome.
How similar studies have performed: Previous research has shown that differences in environmental exposures can significantly impact asthma rates, suggesting that this approach may yield valuable insights.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Lynch, Susan Veronica — University of Arizona
- Study coordinator: Lynch, Susan Veronica
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.