How the immune system helps heal skin wounds
Official title: Innate immune regulation of wound re-epithelialization
Funded at Ut Southwestern Medical Center · NIH-11083611 · Data updated 2026-11-12
This study is looking at how our immune system helps heal skin wounds and how special skin cells work with immune cells to speed up the healing process, with the goal of finding new ways to make wounds heal better for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | May 5, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $236,796 |
| NIH project number | 5R00AR072780-05 |
| Project ID | NIH-11083611 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic wounds or skin injuries, particularly those with conditions that impair healing.
✕Less likely to help
Patients with non-skin related injuries or those who do not have any issues with wound healing may not benefit from this research.
What this research studies
This research investigates the process of wound healing in the skin, focusing on how the immune system influences the repair of skin injuries. It examines the role of adult stem cells in the skin and how they work alongside immune cells to promote healing. The study aims to identify specific molecules produced during skin injury that activate the immune response and facilitate the healing process. By understanding these mechanisms, the research hopes to uncover new ways to enhance wound healing.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for wounds and skin injuries, enhancing healing and recovery for patients.
How similar studies have gone: Previous research has shown promising results in understanding the immune system's role in wound healing, indicating that this approach has potential for success.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Liu, Siqi — Ut Southwestern Medical Center
- Study coordinator: Liu, Siqi
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Understanding how skin cells exchange harmful chemicals to cause injury and wound repair
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.