How the immune environment affects breast cancer in Hispanic/Latino people
The role of immunosuppression in the tumor microenvironment in Hispanic/Latino patients with breast cancer
This project looks at how immune-suppressing cells and signals in tumors differ in Hispanic/Latino adults with breast cancer to help guide better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11143012 on NIH RePORTER |
What this research studies
If you join, researchers will combine your medical records with blood samples and leftover tumor tissue to study immune cells and signals around the tumor. They will run genetic, protein, and other molecular tests (multi-omics) to map differences in the tumor microenvironment. The team will link those lab results to treatment and outcome information to understand why some patients respond differently to immunotherapy. Participation may include active follow-up so researchers can connect lab findings with real-world treatment results.
Who could benefit from this research
Good fit: Adults (age 21 and over) who self-identify as Hispanic/Latino, have a diagnosis of breast cancer, and are willing to provide blood, allow use of tumor tissue, and share their medical records.
Not a fit: People without breast cancer, those who are not Hispanic/Latino, or those unwilling to provide samples or medical records are unlikely to benefit directly from this work.
Why it matters
Potential benefit: Could help doctors tailor immunotherapy and reduce treatment disparities for Hispanic/Latino breast cancer patients.
How similar studies have performed: Research on tumor microenvironments and immunotherapy has led to benefits for some breast cancer patients, but focused studies on Hispanic/Latino populations are still limited.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Roussos Torres, Evanthia Theodosiou — University of Southern California
- Study coordinator: Roussos Torres, Evanthia Theodosiou
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.