How the human brain uses smell to navigate environments
Behavioral and Neural Substrates of Odor-Guided Navigation in the Human Brain
This study is looking at how our brains use smells to help us find our way around and make good choices, and it's for anyone interested in how we navigate our world using our sense of smell.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11003726 on NIH RePORTER |
What this research studies
This research investigates how the human brain processes odor information to help individuals navigate their surroundings. By focusing on the olfactory system, the study aims to understand how smells can guide people toward desirable objects and away from harmful ones. The research employs advanced neurobiological techniques to explore the mechanisms and limitations of odor-guided navigation. Participants may engage in tasks that assess their ability to identify and track odors in various environments.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with Alzheimer's disease or related dementias who experience challenges with navigation and spatial awareness.
Not a fit: Patients who do not have cognitive impairments or those without any difficulties in navigation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of sensory navigation, potentially leading to improved strategies for individuals with navigation difficulties, such as those with Alzheimer's disease.
How similar studies have performed: Previous research in animals has shown promising results in understanding odor-guided navigation, but this approach in humans is relatively novel and untested.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Gottfried, Jay a — University of Pennsylvania
- Study coordinator: Gottfried, Jay a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.