How the human brain forms memories quickly

Human hippocampal contributions to rapid encoding-retrieval interactions during memory formation

NIH-funded research University of Chicago · NIH-11132672

This project aims to better understand how the human brain, specifically the hippocampus, helps us form new memories, especially for people with memory challenges.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11132672 on NIH RePORTER

What this research studies

Many people with conditions like epilepsy, brain injury, or PTSD experience difficulties with memory. This project focuses on how a part of the brain called the hippocampus works with other brain areas to create new memories. We want to learn more about how the hippocampus helps us take in information from our surroundings and turn it into lasting memories. By understanding these basic processes, we hope to pave the way for new ways to help people with memory problems.

Who could benefit from this research

Good fit: This foundational research is relevant to individuals experiencing memory impairment due to neurological or psychiatric disorders affecting the hippocampus, such as epilepsy, brain injury, neurodegeneration, schizophrenia, or PTSD.

Not a fit: Patients without memory impairment or conditions affecting the hippocampus may not directly benefit from this specific foundational research.

Why it matters

Potential benefit: If successful, this work could lead to a deeper understanding of memory formation, which is essential for developing new treatments for memory loss caused by various neurological and psychiatric conditions.

How similar studies have performed: While the hippocampus's role in memory is well-established, this project tests a specific, less understood hypothesis about its real-time involvement during active memory formation.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryCognitive Retention Disorders
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.