NIH-funded research Career grant

How the hippocampus helps us remember and navigate

Official title: Hippocampal Mechanisms of Episodic Memory Recall and their Contribution to Naturalistic Navigation Decisions

Funded at Columbia University Health Sciences · NIH-11067763 · Data updated 2026-11-12

This study is looking at how the brains of black-capped chickadees help them remember where they’ve hidden food and how that memory helps them find it later, which could teach us more about how our own memories work when we make decisions.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startApril 8, 2024
Project endMarch 31, 2026
Funding year2025
Award (this year)$123,191
NIH project number5K99NS136846-02
Project IDNIH-11067763 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research would include individuals experiencing memory decline, particularly those at risk for or diagnosed with Alzheimer's disease.

Less likely to help

Patients with memory impairments unrelated to hippocampal function or those with advanced Alzheimer's disease may not benefit from this research.

What this research studies

This research investigates the role of the hippocampus in episodic memory and navigation using black-capped chickadees as a model. It aims to uncover the neural mechanisms that allow these birds to recall specific memories and make decisions based on those memories, particularly in the context of finding cached food. By studying the activity of neurons in the hippocampus and related brain areas, the research seeks to develop a computational model that explains how memory influences navigation decisions. This could provide insights into how similar processes might work in humans, especially in relation to memory and decision-making.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of memory processes, potentially leading to improved strategies for addressing memory-related conditions such as Alzheimer's disease.

How similar studies have gone: Other research has shown success in understanding memory mechanisms in animal models, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Chettih, Selmaan — Columbia University Health Sciences
  • Study coordinator: Chettih, Selmaan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.