How the hippocampus helps us form and retrieve memories
Human hippocampal contributions to rapid encoding-retrieval interactions during memory formation
['FUNDING_R01'] · UNIVERSITY OF CHICAGO · NIH-10894020
This study looks at how a part of the brain called the hippocampus helps us make and remember memories, especially how it works with other brain areas when we’re trying to learn new things, and it aims to find ways to improve memory for people with conditions like epilepsy, brain injuries, or PTSD.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10894020 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the human hippocampus in the process of forming and retrieving memories, particularly focusing on how it interacts with other brain networks during active information sampling. By examining how the hippocampus supports the binding of information into memories and influences attention, the study aims to uncover mechanisms that could lead to better treatments for memory impairments. Patients with conditions like epilepsy, brain injuries, or PTSD may benefit from insights gained through this research, as it seeks to enhance our understanding of memory formation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with epilepsy, brain injuries, neurodegeneration, schizophrenia, or PTSD who experience episodic memory impairments.
Not a fit: Patients without memory impairments or those whose conditions do not affect the hippocampus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals suffering from memory impairments due to neurological and psychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding the hippocampus's role in memory, suggesting that this approach could yield valuable insights.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VOSS, JOEL L — UNIVERSITY OF CHICAGO
- Study coordinator: VOSS, JOEL L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury, Cognitive Retention Disorders