How the front of the brain helps the visual system focus

Functional organization and spatial resolution of attentional feedback from frontal to visual cortex

NIH-funded research Georgia Institute of Technology · NIH-11290800

This work looks at how signals from frontal brain areas help visual brain regions focus on important spots, using experiments in mice to learn how attention works.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia Institute of Technology NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11290800 on NIH RePORTER

What this research studies

The team will record activity from precisely identified neurons in frontal cortex and multiple visual areas while mice perform tasks that require paying attention to specific locations. They will use modern techniques including multi-area neural recordings and optogenetics to turn specific pathways on or off and map where feedback is sent. The project will relate those neural signals to the animals' attention-related behavior and the retinotopic (spatial) organization of visual cortex. Results will aim to show which frontal-to-visual connections are most precise and effective during spatial attention.

Who could benefit from this research

Good fit: This project does not enroll people now, but its findings may eventually help people with attentional deficits such as ADHD or visual attention problems.

Not a fit: People seeking immediate treatment or wishing to join a human clinical trial will not benefit directly because the experiments are done in mice as basic neuroscience.

Why it matters

Potential benefit: If successful, this could point to specific brain circuit targets that one day lead to better treatments for attention problems.

How similar studies have performed: Prior animal studies using optogenetics and recordings have shown that frontal signals can influence visual processing, and this project builds on those promising methods by measuring multi-area feedback with higher spatial precision.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.