How the dermal sheath influences hair follicle growth and regression
Regulation of catagen regression and progenitor pruning by the dermal sheath
This study looks at how a part of the hair follicle called the dermal sheath helps control hair growth and loss, especially during the phase when hair starts to fall out, and it hopes to find new ways to treat hair loss that could help people like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10880519 on NIH RePORTER |
What this research studies
This research investigates the role of the dermal sheath in the hair growth cycle, particularly focusing on how it regulates the death of progenitor cells during the catagen phase, which is when hair follicles regress. By examining the signals produced by the dermal sheath, the study aims to understand the mechanisms behind hair follicle remodeling and regeneration. The research employs various biological assays to analyze cell communication and signaling pathways involved in these processes. Patients may benefit from insights into hair loss treatments and regenerative therapies based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing hair loss or those interested in hair follicle regeneration.
Not a fit: Patients with hair follicles that are permanently damaged or those not experiencing hair loss may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for hair loss and improved regenerative therapies for hair follicles.
How similar studies have performed: Previous research has shown promising results in understanding hair follicle biology, indicating that this approach could yield significant insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Rendl, Michael — Icahn School of Medicine at Mount Sinai
- Study coordinator: Rendl, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.