How the cerebellum controls precise arm movements
Circuit mechanisms of cerebellar control of reaching movements
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10811961
This study is looking at how a part of the brain called the cerebellum helps control how accurately and precisely we move our arms, using mice to learn more about what happens when this part of the brain doesn't work properly.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10811961 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the cerebellum in controlling the precision and accuracy of arm movements. By studying mice, the researchers aim to understand how information is processed in the cerebellar cortex and transmitted to the cerebellar nuclei, which are crucial for motor control. The study focuses on how specific neural signals influence the timing and execution of reaching movements, particularly in cases where cerebellar dysfunction leads to movement errors. Through advanced techniques, the researchers will analyze the firing patterns of neurons to uncover the mechanisms behind these motor adjustments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cerebellar dysfunction or related movement disorders.
Not a fit: Patients without cerebellar disorders or those whose movement issues are unrelated to cerebellar function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals with cerebellar disorders affecting movement.
How similar studies have performed: Previous research has shown promising results in understanding cerebellar function and its impact on movement, indicating that this approach has potential for success.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PERSON, ABIGAIL L — UNIVERSITY OF COLORADO DENVER
- Study coordinator: PERSON, ABIGAIL L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.