NIH-funded research R01 grant

How the brain represents and generalizes past experiences

Official title: The geometry of neural representations reflecting abstraction in humans

Funded at Columbia Univ New York Morningside · NIH-11066559 · Data updated 2026-11-12

This study is looking at how our brains learn to spot similarities in things we've experienced before, and it's for healthy people who want to help us understand how motivation and different learning speeds affect this process.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia Univ New York Morningside
NIH-funded
Lab location1 site (New York, United States)
Project startMay 1, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$555,821
NIH project number5R01MH130068-03
Project IDNIH-11066559 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation are healthy adults interested in cognitive neuroscience and learning processes.

Less likely to help

Patients with severe cognitive impairments or neurological disorders may not benefit from this research.

What this research studies

This research investigates how the human brain learns to identify shared features from past experiences to simplify complex environments. By using functional MRI (fMRI), healthy participants will engage in a learning task that involves recognizing patterns among various stimuli. The study aims to understand how different learning timescales and motivational states influence the brain's ability to generalize information. This approach combines insights from previous studies in non-human primates with advanced neuroimaging techniques.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of cognitive processes, potentially leading to improved treatments for conditions related to abnormal psychology.

How similar studies have gone: Previous research in non-human primates has shown promising results using similar methodologies, suggesting potential for success in human studies.

Where this research is happening

  • Columbia Univ New York Morningside
    New York, United States
    Active

Researchers

  • Principal investigator: Shohamy, Daphna — Columbia Univ New York Morningside
  • Study coordinator: Shohamy, Daphna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.